NFL Week 5 Odds and Betting Lines: Chiefs -5.5 vs Saints on MNF

The schedule is already into October, giving the NFL Week 5 odds a dash of "pumpkin spice" flavoring.

The NFC South started the week when the Tampa Bay Buccaneers and Atlanta Falcons finally provided fans with a TNF game worth watching. Now, the week wraps with the Kansas City Chiefs favored at home over the New Orleans Saints on Monday Night Football.

Here are the NFL odds for Week 5 on Sunday night.

NFL Week 5 Odds

These are the odds for Week 5, headlined by the Chiefs and Saints battling on Monday Night Football.

Matchup	Time (E.T.)	Odds
Buccaneers vs Falcons	Thursday 8:15 p.m. Prime	Falcons -2 O/U 43.5
Jets vs Vikings	Sunday 9:30 a.m. NFL Network	Vikings -2.5 O/U 40.5
Browns vs Commanders	Sunday 1:00 p.m. FOX	Commanders -3.5 O/U 43.5
Ravens vs Bengals	Sunday 1:00 p.m. CBS	Bengals +2.5 O/U 48.5
Bills vs Texans	Sunday 1:00 p.m. CBS	Texans -1 O/U 47
Colts vs Jaguars	Sunday 1:00 p.m. CBS	Jaguars -3 O/U 46
Panthers vs Bears	Sunday 1:00 p.m. FOX	Bears -4 O/U 41
Dolphins vs Patriots	Sunday 1:00 p.m. FOX	Patriots -1 O/U 36
Cardinals vs 49ers	Sunday 4:05 p.m. FOX	49ers -7.5 O/U 49
Raiders vs Broncos	Sunday 4:05 p.m. FOX	Broncos -2.5 O/U 35.5
Packers vs Rams	Sunday 4:25 p.m. CBS	Rams +3 O/U 48.5
Giants vs Seahawks	Sunday 4:25 p.m. CBS	Seahawks -7 O/U 42.5
Cowboys vs Steelers	Sunday 8:20 p.m. NBC	Steelers -2.5 O/U 44
Saints vs Chiefs	Monday 8:15 p.m. ESPN	Chiefs -5.5 O/U 43

Byes this week:
Lions,  Titans, Eagles, Chargers

Buccaneers vs. Falcons odds

Opening line

• Falcons -2.5
• Over/Under 43
• View full Buccaneers vs. Falcons odds and matchup
• Read our Buccaneers vs. Falcons picks and predictions

Both teams were victorious in Week 4, but the Bucs looked especially strong in a one-sided win over Philadelphia. The Falcons scored 26 points but did so without an offensive TD versus New Orleans. That's kept this opener below a field goal with Atlanta hitting the board at -2.5. The total opened at 43 points. With money coming in on the Bucs, that spread has shrunk to -1.5 at most books, though you can find Tampa +2 on Thursday morning.

Also see: full Thursday Night Football odds

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Jets vs. Vikings odds

Opening line

• Vikings -2.5
• Over/Under 41.5
• View full Jets vs. Vikings odds and matchup
• Read our Jets vs. Vikings picks and predictions

The Jets looked bad in a home loss to Denver while the Vikings improved to 4-0 with a strong showing at Green Bay. Books opened Minnesota as a 2.5-point neutral-site favorite in London with the total at a low 41.5 O/U. The spread has held firm and the total has bounced around the opener, now sitting at 41 on Sunday morning.

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Browns vs. Commanders odds

Opening line

• Commanders -3
• Over/Under 43.5
• View full Browns vs. Commanders odds and matchup
• Read our Browns vs. Commanders picks and predictions

Washington could be the hottest team in the NFL with 80 points in the past two games. That's more than Cleveland has scored all season. Books opened the Commanders as field-goal faves at home and that quickly jumped to -3.5, but buyback on Cleveland has this spread at a field goal on Sunday. The total hit the board at 43.5 points and has returned to its opening number after hitting 44.5.

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Ravens vs. Bengals odds

Opening line

• Bengals +2.5
• Over/Under 48.5
• View full Ravens vs. Bengals odds and matchup
• Read our Ravens vs. Bengals picks and predictions

The Ravens looked impressive on Sunday night, rolling through the Bills and opening as 2.5-point favorites after look-ahead lines had this AFC North rivalry as short as Baltimore -1.5. You can find the Ravens between -1.5 and -2.5 on Sunday morning. The total opened at 48.5 O/U, jumped to 50.5 across the board, and has settled back at 48.5 points.

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Bills vs. Texans odds

Opening line

• Texans -1.5
• Over/Under 46.5
• View full Bills vs. Texans odds and matchup
• Read our Bills vs. Texans picks and predictions (coming soon)

Buffalo got bullied by Baltimore on Sunday night and suffered its first loss of the season. Houston escaped with a last-minute win over Jacksonville and stays home for this huge AFC showdown. The Texans opened as 1.5-point favorites with the total hitting the board at 46.5 O/U. Most of the Houston -1.5 lines have dipped to 1.0 while the total is hovering between 47.5 and 48 on Sunday.

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Colts vs. Jaguars odds

Opening line

• Jaguars -2.5
• Over/Under 46
• View full Colts vs. Jaguars odds and matchup
• Read our Colts vs. Jaguars picks and predictions

Jacksonville opened as a 2.5-point home favorite and jumped to -3 with injuries to the Colts' top offensive weapons. Quarterback Anthony Richardson and RB Jonathan Taylor are out for Week 5, which has this line creeping to Jaguars -3.5 on Sunday morning. This total opened at 46 points and is down to 45.5 O/U.

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Panthers vs. Bears odds

Opening line

• Bears -4.5
• Over/Under 43
• View full Panthers vs. Bears odds and matchup
• Read our Panthers vs. Bears picks and predictions 

The Bears defense continues to come up big, leading Chicago to a win in Week 4. The Bears opened as a 4.5-point home chalk versus Carolina, which has shown a little fight with veteran QB Andy Dalton under center. That spread has dropped to Chicago -3.5 and -4 at most books. This total opened at 43 points at most books and is between 41 on Sunday.

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Dolphins vs. Patriots odds

Opening line

• Patriots -1.5
• Over/Under 36.5
• View full Dolphins vs. Patriots odds and matchup
• Read our Dolphins vs. Patriots picks and predictions

A bad loss on Monday night had Miami opening as a 1.5-point underdog in New England this weekend. That number jumped the fence with action on the Dolphins, making a Miami a -1 favorite on Sunday morning. With both AFC East teams struggling to score, the total hit the board at 35.5 O/U and is down to as low as 35 O/U.

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Cardinals vs. 49ers odds

Opening line

• 49ers -7.5
• Over/Under 49
• View full Cardinals vs. 49ers odds and matchup
• Read our Cardinals vs. 49ers picks and predictions

Two bad losses from Arizona have the Cardinals getting 7.5 points when they come to Levi's Stadium in Week 5. San Francisco continues to push through injury issues and is expected to have LB Fred Warner (ankle) in Week 5. The Over/Under opened at 49 points and climbed to 50 on Sunday night before trimming to 48.5 O/U on Sunday.

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Raiders vs. Broncos odds

Opening line

• Broncos -1.5
• Over/Under 37
• View full Raiders vs. Broncos odds and matchup
• Read our Raiders vs. Broncos picks and predictions

A win is a win, even if it's ugly. Denver stole a road victory in New York and is now a 3-point home favorite versus Las Vegas in Week 5. The Raiders beat the Browns as home underdogs, and WR Davante Adams' out status has pushed this total around. The Over/Under opened at a low 37 points and has only gotten lower, sitting at 35.5 on Sunday.

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Packers vs. Rams odds

Opening line

• Rams +3.5
• Over/Under 46
• View full Packers vs. Rams odds and matchup
• Read our Packers vs. Rams picks and predictions

Jordan Love was back under center for the Packers in Week 4. Despite the loss to Minnesota, the Cheeseheads opened -3.5 on the road in Los Angeles but have been bet down to -3 with missing pieces at receiver. This total opened at 46, jumped up to 47.5 quickly on Sunday night, and has continued to rise as high as 49 on Sunday morning.

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Giants vs. Seahawks odds

Opening line

• Seahawks -5.5
• Over/Under 41.5
• View full Giants vs. Seahawks odds and matchup
• Read our Giants vs. Seahawks picks and predictions

Seattle didn't survive a shootout in Detroit on Monday and now hosts the Giants as 7.5-point faves in Week 5. New York has a big rest advantage, having played last Thursday with the Seahawks coming into a short week, but will be without star rookie WR Malik Nabers, which moved this spread from +5.5 to +7.5 for New York. The total opened at 41.5 O/U and has since jumped 42.5 as of Sunday morning.

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Cowboys vs. Steelers odds

Opening line

• Steelers -2.5
• Over/Under 42
• View full Cowboys vs. Steelers odds and matchup
• Read our Cowboys vs. Steelers picks and predictions

Pittsburgh suffered its first loss of the season in Week 3 but opened as a short chalk at home to Dallas for Sunday Night Football. Money on the Cowboys originally slimmed this spread from -2.5 to -1.5 but buyback on the Steelers has shifted it back to the opening number. The total opened at 42 points and is now available between 43.5 and 44 points. Dallas is on a mini-bye after winning on Thursday but lost key defenders Micah Parsons and Demarcus Lawrence.

Also see: full Sunday Night Football odds

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Saints vs. Chiefs odds

Opening line

• Chiefs -5
• Over/Under 43.5
• View full Saints vs. Chiefs odds and matchup
• Read our Saints vs. Chiefs picks and predictions

Kansas City keeps rolling but will do so without WR Rashee Rice, who suffered a bad knee injury in Week 4. The Chiefs opened as 5-point favorites on Monday Night Football with some KC -5.5 lines the most common Sunday. New Orleans has come back to earth after a hot start, losing its last two outings. This total opened at 43 points and is still there a week later.

Also see: full Monday Night Football odds

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Best NFL bets this week

Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!

More weekly NFL odds content

• Week 1 odds
• Week 2 odds
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