Texans vs Chiefs Predictions, Picks, and Best Bets for NFL Week 16

Jason Logan expects the Texans to call Joe Mixon's number early and often vs. Kansas City.

Jason Logan: Senior Betting Analyst at Covers
Jason Logan ? Senior Betting Analyst
Dec 21, 2024 ? 11:38 ET ? 4 min read
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This article contains predictions for an old game!

Latest NFL Picks
Kansas City Chiefs Patrick Mahomes Houston Texans CJ Stroud NFL
Photo By - Imagn Images. Pictured: Patrick Mahomes and CJ Stroud.

The Houston Texans come to Arrowhead Stadium today for a gut-check game against the Kansas City Chiefs. Kickoff is at 1:00 p.m. ET on NBC.

My Texans vs. Chiefs predictions explain why Joe Mixon is the key to the visitors' success in what will be a gut-check game for a Houston side out to prove it belongs in the playoffs.

Here are my best NFL picks for Saturday, December 21.

Texans vs Chiefs predictions

Texans vs Chiefs spread prediction

If you read my NFL Underdogs column, you’d see I had faith in the Kansas City defense and backup QB Carson Wentz, betting the Chiefs at +2.5. Now, with Mahomes trending toward playing, this spread has swung to K.C. -3.5.

I bet on the Chiefs -4 last week, with the betting market finally reacting to Kansas City’s inability to cover the spread. That matchup with the Browns was the wake-up call for K.C., serving as a stiff cup of coffee to get this team playing at postseason levels.

With the vig on Kansas City -3.5 ticking upward, I want to bet the Chiefs below the undervalued key number of -4.

Texans vs Chiefs moneyline prediction

The odds for this Saturday's showcase have fluctuated more than my waistline this holiday season. Instead of cookies and beer driving those changes, it’s been the health of Kansas City quarterback Patrick Mahomes keeping oddsmakers on their toes.

Mahomes suffered a high ankle sprain in the win over Cleveland in Week 15, leaving his status in doubt for this short week. That saw Houston opened as a slim road favorite, with Texans moneyline as high as -164.

But with Mahomes back at practice in full capacity, those odds flipped, and the Chiefs are now -172 home favorites to win outright. That gives K.C. an implied win probability of 63%.

Even before the update on Mahomes’ ankle, I believed Kansas City could still win outright. With the future Hall of Famer back under center, the Chiefs are an even stronger side at home on Saturday.

Texans vs Chiefs Over/Under prediction

With Mahomes questionable, this Over/Under opened at 40.5 and slipped to 39.5 O/U. Once Mahomes returned to practice on Tuesday afternoon, this number was boosted to as high as 43.5 O/U before buyback on the Under knocked it back to 41.5 points.

It’s a strange movement, considering the spread swung nearly a touchdown with Mahomes looking healthy. What that tells us is that oddsmakers have a lot of faith in the Chiefs' defense facing a Texans attack that doesn’t produce on the road.

Houston QB C.J. Stroud has only played in nine outdoor games in this pro career, and his passing metrics take a nose dive in those open-air venues. Saturday’s forecast calls for temperatures in the high 30s in Arrowhead Stadium.

I’ll lean Under at 41.5 points.

My best bet
Joe Mixon Over 60.5 rushing yards (-115 at BetMGM)

My analysis
The Houston Texans need a big day from running back Joe Mixon, especially on the ground. 

The Kansas City Chiefs will be coming after QB C.J. Stroud with one of the more blitz-happy schemes in the NFL. In order to keep that defense honest and play a little “keep-away” from Mahomes & Co., offensive coordinator Bobby Slowik will be calling on No. 28 early and often.

Mixon sits 10th in total rushing attempts despite playing in only 11 games due to injury. He’s made the most of those carries, running for 910 yards — including seven games of 100+ gains on the ground.

He carried the ball only 12 times in the win over Miami last Sunday (picking up just 23 yards) due to suffering an ankle injury on a hip-drop tackle. That forced him on the sideline for a while and stunted his production on the ground once he returned.

Mixon popped up on the Texans’ injury report this week, nursing that sore ankle. But his limited work in practice is just for rest and recovery purposes, as the running back says he’ll definitely play on Saturday.

Kansas City’s run defense has gotten pushed around in recent weeks, allowing 538 total rushing yards over the past five games, with foes picking up 4.4 yards per carry. Last week, Cleveland carried the ball just 21 times for 139 yards rushing.

Mixon normally sees close to 20 rushing attempts per game, and the Week 16 player projections come in around that average. His yardage on Saturday is forecast to be very positive.

Mixon’s models range from 69 yards to a ceiling of 87 yards against the Chiefs, with my number coming out to 78 yards on the ground from the veteran RB. That’s well beyond his rushing yard total for Week 16, with the Over/Under at 60.5 yards.

Texans vs Chiefs same-game parlay

Joe Mixon 50+ rushing yards

DeAndre Hopkins 50+ receiving yards

Chiefs moneyline

Mixon will get plenty of carries and some projections have him flirting with more than 80 yards on the ground.

DeAndre Hopkins has quickly become one of Mahomes’ favorite targets. His forecasts call for more than 50 yards through the air against his former club.

Kansas City has played in a lot of tight games, so we’ll sidestep the growing spread and take the home team to win outright on Saturday.

Learn how to bet a same-game parlay with these helpful tips and strategies.

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More NFL picks and odds from Covers


Texans vs Chiefs odds

Texans vs Chiefs live odds

Texans vs Chiefs opening odds

  • Spread: Houston -2.5 (-115) | Kansas City +2.5 (-105)
  • Moneyline: Houston -140 | Kansas City +115
  • Over/Under: Over 40.5 (-110) | Under 40.5 (-110)

Odds courtesy of BetMGM

Texans vs Chiefs spread and Over/Under analysis

  • The look-ahead line for this AFC clash was Kansas City -3.5 before Mahomes injured his ankle in Week 15. The official opening odds hit the board with Houston as a 2.5-point road favorite and jumped to -3 before sharp money bought back K.C. at the field goal.
  • The total opened at 40.5 points and slipped as low as 39.5 O/U. Upon Mahomes’ updated status, the number jumped to 43.5 before buyback on the Under trimmed the total to the current spot of 41.5 points.
  • According to the latest Covers Consensus data, 54% of picks are on the Texans, while 56% of total picks are taking the Over.

Texans vs Chiefs betting splits

According to BetMGM, these are the most popular NFL player props for the early Saturday kickoff by volume of tickets:

  • Joe Mixon Over 60.5 rushing yards (-115)
  • Isiah Pacheco Under 1.5 receptions made (-120)
  • Xavier Worthy Over 3.5 receptions made (+105)
  • Xavier Worthy Over 1.5 rushing yards (-115)
  • Noah Gray Under 2.5 receptions made (-105)

Texans vs Chiefs betting trend to know

The Texans are 4-13 Over/Under in outdoor games the past three seasons, including 3-8 O/U the past two years (since they drafted Stroud) and 1-3 O/U outside in 2024. Find more NFL betting trends for Texans vs. Chiefs.

Texans vs Chiefs game info

Location: Arrowhead Stadium, Kansas City, MO
Date: Saturday, 12-21-2024
Kickoff: 1:00 p.m. ET
TV: NBC

Texans vs Chiefs latest injuries

Texans vs Chiefs weather

Monitor gametime conditions with our live NFL weather info and learn how weather impacts NFL betting.

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Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, lead NFL betting analyst “JLo” has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike.

Since joining the Covers team back in 2005, he’s honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet.

He is under center for Covers during NFL season as our top NFL expert, taking the points in his infamous “NFL Underdogs” column and representing the Covers Community at the Super Bowl. While he lives for football season, Jason’s first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns.

On top of being a mainstay in media from coast to coast – WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio – he’s had his analysis featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers’ flagship podcast, The Sharp 600.

His best advice for bettors new and old is “Handicapping isn’t a ‘one size fits all’ process. The impact and importance of information varies from bet to bet. Treat each wager different than the last.”

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