We have a fantastic edition of Sunday Night Football in Week 13 with the San Francisco 49ers taking on the Buffalo Bills. and with it comes some strong 49ers vs. Bills anytime touchdown picks.
I feel good about this batch of anytime TD selections for SNF, so let's dig right in as I tell you why Jauan Jennings and James Cook should be getting more respect in this market in my free NFL picks for December 1.
49ers anytime touchdown pick
Jauan Jennings anytime touchdown
+375 at bet365
Jauan Jennings has just one touchdown in his last three games, but the amount of run he's gotten in that span suggests he's the best bet on the San Francisco 49ers side to score six points on Sunday.
Jennings has been targeted 29 times in his last three games, hauling in 22 of those passes 224 yards with only one score. George Kittle has three touchdowns in the same span, but he'll be hard-pressed to stump a Buffalo Bills defense that's allowed only three touchdowns to tight ends all year.
Christian McCaffrey is the shortest price of any Niners player to break the plane, but that's based more on reputation than on his play this year as he's been blanked in his first three games off the IR. Take Jennings while you still can at this price based on his elevated status on the depth chart.
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Bills anytime touchdown pick
James Cook anytime touchdown
-110 at bet365
I'm stunned James Cook isn't a shorter price in the Week 13 player props, but I won't look a gift horse in the mouth — he tops my 49ers vs. Bills predictions to score a touchdown on Sunday Night Football.
Cook leads all Bills players by a wide margin with 11 total touchdowns this season, with 10 coming on the ground. That spells trouble for a San Francisco defense that's allowed 12 rushing scores to RBs this season, the third-worst mark in football.
Cook has broken the plane at least once in five of his last six games, including his two-score performance vs. the Chiefs in Week 12. He's also averaged just under 15 touches per game over his last four outings, so Cook will get plenty of quantity as well as quality when it comes to scoring chances.
If you want to chase a longer price on the Bills, you could do worse than Khalil Shakir at +175. The receiving TDs are comically spread out on the Bills, with 11 different men hauling in a Josh Allen pass for six points (five different multi-TD scorers), but Shakir (two scores) has a healthy lead in receptions over Dalton Kincaid, 56-34.
Shakir should not be tied in price with Amari Cooper and Keon Coleman based on their inferior body of work in 2024.
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